David Villa scored twice as Barcelona ripped Jose Mourinho's Real Madrid apart in a 5-0 rout Monday to go top of the standings thanks to a record fifth straight “clasico” win over its bitter rival.

Xavi Hernandez and Pedro Rodriguez put the defending champion 2-0 ahead inside 18 minutes before Villa scored a second-half brace. Substitute Jeffren Suarez scored in the 90th to seal it in front of nearly 100,000 fans at the Camp Nou stadium.

Barcelona's speed and quick-touch passing game frustrated Madrid throughout as it recorded its biggest national derby victory since a 5-0 win here during the 1993-94 season.

A miserable night for Madrid was compounded in the final seconds when Sergio Ramos was sent off for shoving Lionel Messi as the visiting side's frustrations boiled over.

Barcelona now leads Madrid by two points with 34 points from 13 games after a seventh straight league win.

Former Chelsea and FC Porto coach Mourinho suffered his worst ever loss to stay winless in six trips to Barcelona. He had never lost by more than three goals before.

The contrast with the Portuguese coach's last visit to the Camp Nou couldn't be more striking. In April, his Inter Milan side knocked the Catalans out of the Champions League in the semifinals on its way to winning the title.

Mourinho now has his work cut out to wrestle the league trophy away from Barcelona, the two-time defending champion, and return silverware to the Spanish capital. Madrid hadn't lost in 26 games, stretching to its last defeat by Barcelona in April.

Andres Iniesta picked out Xavi as he streaked between two defenders and the ball flicked off the Spain midfielder's heel before he reacted quickly to direct it past Iker Casillas for the 10th-minute opener.

Madrid sat back and looked to attack on the break with Cristiano Ronaldo and Angel Di Maria threatening from the flanks. Barcelona 'keeper Victor Valdes got a hand up to tip Di Maria's rising shot over the bar in the 12th.

Pedro capped a mesmerising 22-pass buildup to make it 2-0 as he pushed a loose ball into open goal after Casillas failed to hang on to Villa's dangerous ball in from the left. Pedro nearly had a second in the 27th after bursting free into the area along the right but Casillas was out quickly to cut down the angle and clear.

Madrid's frustration and the tension of the match came to a boil in the 31st when both benches leapt to their feet after Ronaldo shoved Pep Guardiola when the Barcelona coach didn't hand over the ball for a throw-in.

Even the diminutive Iniesta was in Ronaldo's face. The Portugal forward and Valdes ended up with the yellow cards. Ronaldo’s free kick took a slight deflection wide in the 34th and he failed to earn a penalty after clashing with Valdes in the race for the subsequent loose ball.

Madrid got physical in a bid to slow the game and regain its composure. Defender Ricardo Carvalho clashed with Messi in the 45th but it was the Argentine winger who got the yellow card for gamesmanship.

But Messi had no problem finding gaps to create both of Villa's goals in near identical plays down the left side. The speedy winger nicknamed “The Flea'” ran circles around Madrid while Ronaldo failed to make an impact in the matchup of two of the world's best players.

Villa got behind Pepe in the 55th to receive from the Argentine and slot past Casillas, who was again on his own three minutes later when Villa slotted under him for his eighth of the season. Mourinho watched on stone-faced from Madrid's bench.

A deflated Madrid failed to create any danger after that as Suarez capped the rout in injury-time before Ramos was sent off for Madrid.