New diabetes drug ‘flushes’ away sugar

Mar 31, 2013 |

The US Food and Drug Administration on Friday approved a first-of-its-kind diabetes drug from Johnson & Johnson that uses a new method to lower blood sugar — flushing it out in patients’ urine.

The agency cleared J&J’s Invokana tablets for adults with Type-2 diabetes. The once-a-day medication works by blocking the kidneys from reabsorbing sugar, which occurs at higher levels in patients with diabetes than in healthy patients. Regulators highlighted the drug as the first in a new class of medications that could help address the growing diabetes epidemic. Analysts estimate Invokana could eventually grow into a blockbuster drug, generating more than $1 billion in sales annually for J&J.
People with Type-2 diabetes are unable to properly break down carbohydrates, either because their bodies do not produce enough insulin or have become resistant to the hormone, which controls blood sugar levels.
These patients are at higher risk of heart attacks, kidney problems, blindness and other serious complications.

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