Finger bone genome leads to a new human ancestor

Newly-crowned Miss Earth 2010 Nicole Faria arrives at Bengaluru international airport on Thursday. 	PHOTO: PTI

Newly-crowned Miss Earth 2010 Nicole Faria arrives at Bengaluru international airport on Thursday. PHOTO: PTI

Researchers identified on Wednesday a previously unknown relative to the Neanderthal who lived in Asia 30,000 to 50,000 years ago and interbred with the ancestors of Papua New Guinea inhabitants.
Scientists were able to extract the entire genome of the group known as the Denisovans using only a finger bone and a wisdom tooth found in Siberia’s Denisova Cave in 2008.
An earlier mitochondrial genome sequence conducted in March provided little information about the hominid other than it was part of a population long diverged from humans and Neanderthals.
The finger bone and tooth are now known to come from a female from the hominid group that shared its ancient origin with the Neanderthal but quickly diverged.
Unlike the Neanderthals, the Denisovans did not contribute to the genetic pool of modern Eurasians, but share up to one twentieth of their DNA with the inhabitants of Papua New Guinea and islands northeast of Australia.
This suggests there was interbreeding between the Denisovans and the ancestors of the Melanesians, the researchers said in a study published in Thursday’s edition of the British magazine Nature.
“The story now gets a bit more complicated,” said study co-author Richard Green, an assistant professor of biomolecular engineering in the Baskin School of Engineering at the University of California, Santa Cruz.
“Instead of the clean story we used to have of modern humans migrating out of Africa and replacing Neanderthals, we now see these very intertwined story lines with more players and more interactions than we knew of before.”
The international research team was led by Svante Paabo of the Max-Planck Institute for Evolutionary Anthropology in Leipzig, Germany. Researchers believe the Neanderthals and Denisovans migrated from Africa around half a million years ago.

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